Panthers coach Ivan Cleary has reduced his squad to face Newcastle Knights at McDonald Jones Stadium on Saturday.
Josh Mansour has been ruled out with a minor shoulder (AC joint) injury, with Malakai Watene-Zelezniak named as his replacement on the wing.
Tim Grant has also been omitted and will play for the Panthers Canterbury Cup side against Newcastle.
CATCH THE CDC TRAVEL PANTHER BUS TO NEWCASTLE
Final Word with Ivan: Round 2
Panthers v Knights
McDonald Jones Stadium
5.30pm Saturday 23 March
1. Dylan EDWARDS - sponsored by Lendcorp
21. Malakai WATENE-ZELEZNIAK - sponsored by Daily Press
3. Dean WHARE - sponsored by Volvo Cars Penrith
4. Waqa BLAKE - sponsored by OAK Plus
5. Dallin WATENE-ZELEZNIAK - sponsored by Fornari's Interior Linings
6. James MALONEY - sponsored by Soneta Plumbing
7. Nathan CLEARY - sponsored by Tuff Mouthguards
8. James TAMOU - sponsored by Signace
9. Sione KATOA - sponsored by Hertz
10. Reagan CAMPBELL-GILLARD - sponsored by HIX Group
11. James FISHER-HARRIS - sponsored by Zoo Fitness
12. Isaah YEO - sponsored by Chemtools
13. Hame SELE - sponsored by Stylus Blinds
14. Wayde EGAN - sponsored by Chardon & Abbott Home Loans
15. Frank WINTERSTEIN - sponsored by Protech Locksmiths
16. Moses LEOTA - sponsored by Potter Automotive
17. Jack HETHERINGTON - sponsored by Bidfood
18. Jarome LUAI - sponsored by CETNAJ Dural/Rouse Hill
20. Liam MARTINĀ - sponsored by Worldwide Parramatta