Panthers playmaker Nathan Cleary will be sidelined for at least four weeks as he rehabilitates a shoulder injury suffered in Origin II last Sunday.
Cleary suffered the injury to his right shoulder during the first half of the clash at Suncorp Stadium.
Having now received specialist medical advice, the club believes a period of rehabilitation is the best course of action at this point in time.
Panthers coach Ivan Cleary has named Matt Burton in the halves alongside Jarome Luai for Friday's Battle of the West at BlueBet Stadium.